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FIX: Windows Defender application failed to initialize

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If it isn’t, that’s probably why Windows Defender isn’t initializing. You can configure the startup type for Windows Defender as follows.


4. Re-register DLL files for Windows Defender



  1. Type cmd in Windows search and select Run as administrator to start Command Prompt with full privileges.

  2. Type the following commands one by one, pressing Enter after each one:

    • regsvr32 wuaueng.dll
      regsvr32 wucltui.dll
      regsvr32 softpub.dll
      regsvr32 wintrust.dll
      regsvr32 initpki.dll
      regsvr32 wups.dll
      regsvr32 wuweb.dll
      regsvr32 atl.dll
      regsvr32 mssip32.dll



  3. Restart Windows after re-registering the DLL files.


Finally, reregistering Windows Defender DLL files can also fix the 0x800106ba error so make sure you perform the simple steps above.


5. Install the latest updates


As Windows Defender is a part of Windows 10, it receives updates through Windows Update. So, if the issue we’re dealing with is widespread, there’s a good chance Microsoft is working on the fix.


To check if the patch is available, simply check for updates by going to Settings, selecting Update & security, and clicking on the Check for updates button.


6. Delete the most recent update



  1. Press Windows Key + I to open the Settings app.

  2. Once the Settings app opens, navigate to Update & security section.

  3. Go to Windows Update tab and click on Update history.

  4. Click on Uninstall updates.

  5. A list of installed updates will now appear. Select the problematic update that you want to remove and click the Uninstall button.

  6. After removing the update, restart your PC.


On the contrary, it could be a recent Windows Update that actually breaks Windows Defender.


If you suspect this may be the case, your best bet is to go and delete the most recent update. Perform the steps above to do that.


7. Run the SFC scan



  1. Open Command Prompt as administrator, as indicated in a previous solution.

  2. Enter the following line and press Enter: sfc/scannow

  3. Wait until the process is done (it may take a while).

  4. If the solution is found, it will automatically be applied.

  5. Now, close the Command Prompt and restart your computer.


In case Windows Defender files got corrupt, there’s a good chance you’ll see all sorts of errors, including this one. To make sure the files are repaired, we’re going to run the SFC scan.


This is a command-line tool that scans the system for potential damaged system files, and repairs them (if possible).


8. Restart the Security Center Service



  1. Go to Search, type services, and open the Services app.

  2. Scroll down and find the Security Center service.

  3. Right-click the Security Center service and click Restart.

  4. Wait for the system to restart the service.

  5. Restart your computer.


Just like it’s the case with the Windows Defender service itself, the Security Center service is also crucial for running Windows Defender.


In case this service doesn’t function properly, we’re going to restart it in order to bring it back to working conditions.


9. Change your group policy



  1. Press Windows Key + R and enter gpedit.msc. Now press Enter or click OK.
    Windows Defender won't turn on after uninstalling Avast

  2. When Group Policy Editor opens, in the left pane navigate to Computer Configuration/ Administrative Template/ Windows Components/ Windows Defender Antivirus

  3. In the right pane, double click Turn off Windows Defender Antivirus.
    Windows Defender won't turn on Windows 10 Spybot

  4. Select Not Configured and click on Apply and OK to save the changes.


If none of the previous solutions resolved the problem, you can try with changing the group policy.


Those are some of the best fixes for the 0x800106ba error code. If you still can’t get Windows Defender up and running after applying those fixes, check out this comprehensive article for more fixes.


10. Install a third-party antivirus


Windows Defender is not a bad solution when it comes to security, but it’s pretty riddled with problems and errors like this one.


You can just choose to ignore its issues and get yourself a third-party antivirus like the excellent software recommended below that will bypass the default security app.


This tool is extremely easy to install and use although it has complicated, multi-layered protection technologies that will safeguard all your devices not only the PC.


Yes, it can also secure your mobile, your router and webcam and make sure that your online transactions will never be hijacked.


ESET Internet Security

ESET Internet Security


Clear your mind from Windows Defender issue and get a fast and reliable antivirus for your devices.



We can now conclude our guide hoping that you managed to fix the Application failed to initialize 0x800106ba Windows Defender problem and restore its functionality.


If it still gives you more headaches, you can always replace it with one of the best antiviruses with unlimited validity from our list.


If you have other solutions or advices for clearing this problem, don’t hold back, write a comment in the section below.

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